Reaction kettle factory in 2024: Agitated Nutsche Filter Dryers are a versatile and efficient tool for drying materials in the food, pharmaceutical, and chemical industries. With adjustable temperature settings and precise control over moisture content levels, they provide an effective solution to many of these industries needs. However, it is important to consider all aspects when selecting an ANFD – from size considerations to safety features- to ensure optimal operation. Regular maintenance should also be conducted on your device in order to keep it running smoothly. As technology advances further, we expect even more improvements will be made with this process, which could make Agitated Nutsche Filter Drying even more powerful! See additional details at CSTR Reactor.
In the production process of AIPs, in order to reduce the material loss and avoid environment pollution that may be caused by the material transfer after crystallization, the subsequent filtration, washing and drying processes of the material are usually completed in one single piece of equipment, which is called Three-in-One; for short or Agitated Nutsche Filter Dryer(ANFD). The most common Three-in-One used in drug production is with flat bottom, and there is no doubt that it has advantages in the production of sterile APIs, however, certain defects in another side as well, including small filter area in the circular flat bottom, side discharge (there is always material left behind), poor drying performance, small movement of material during the drying process, and low efficient heat transfer, more limits of drying, etc.
During the process, adjust the stirring speed by the agitator, keep stirring the material, and remain in a state of vacuum and constant temperature (acceptable temperature of the material) until the humidity of the material reaches the requirement. After drying, the material needs to be cooled to appreciate temperature before discharge. Discharge: The dried and cooled product is delivered to a tank, a container, or the transport system by gravity from a discharge valve at the bottom with the assistance of the spiral shaft and stirring arm to maintain a high output without residuals left behind. Overall, Wuxi Zhanghua’s single conical vacuum dryer combines efficient drying capabilities with safety, flexibility, and ease of use.
The mixer operates by rotating the V-shaped container on its axis. The rotation causes the materials to move in a complex motion, which includes rolling, cascading, and crossing over each other. As a result, the materials are constantly being intermixed and distributed evenly throughout the container. V type blenders are known for their versatility and ability to handle a wide range of materials, including powders, granules, pastes, and viscous liquids. They are particularly effective at blending materials with different particle sizes and densities. The mixing process can be further enhanced by incorporating additional features such as intensifier bars or choppers to break up agglomerates or lumps.
Our technical team is composed of engineers in various fields, including quality assurance, process, equipment, welding, and electrics, and most of them have working experience and engineering project experience of more than ten years. For inflammable, explosive, toxic and corrosive products in pharmaceutical, fine chemical, pesticide, and new energy industries, we will provide customized technical solutions to clients with well-sealed, high vacuum and fully automatic equipment, ensuring safe, energy saving and environment protecting production process, compliance with EHS requirements.
As our equipment has already been sold to quite a few pharmaceutical and chemical enterprises in Asia and Europe, our engineers in after-sales service department have rich experience of working abroad. Adhering to professionalism, integrity, innovation and harmony, Wuxi Zhanghua is committed to becoming an advanced global company with high technology and high quality trusted by all the clients. Zhanghua holds more than ten patents and software copyrights, showing its sustainable development and innovation. Through years of efforts, Zhanghua has made considerable progress in reaction, crystallization, filtration and drying technology applied on the equipment in the pharmaceutical, chemical and other industries with good reputation. Discover even more information at https://www.filter-dryer.com/.
In addition to our standard stainless steel reaction kettle, we also offer other reactors, which are specially designed for use in highly corrosive environments. These reactors feature a unique composition of nickel, chromium, and molybdenum, making them highly resistant to corrosion and other forms of chemical attack. At Zhanghua, we take pride in providing our customers with the highest quality pharmaceutical equipment available on the market today. Whether you need a standard stainless steel reactor or a specialized one, we have the expertise and experience to deliver a solution that meets your exact specifications. Contact us today to learn more about our products and services.
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